Alanine transaminase (ALT)


Statland BE, Winkel P and Bokelund H, 1973, Clin Chem, 19, 1374-9 , Factors contributing to intra-individual variation of serum constituents: 1. within-day variation of serum constituents in healthy subjects


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand D
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score D4
Comment Method different from IFCC

Item Details

Parameter Score
Matrix Serum
Measurand Alanine transaminase (ALT)
Unit U / L
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 11
Number of Subjects included in BV estimation 11
Ethinicity Caucasian
Age Mean / Median
Age Min 21.0
Age Max 27.0
Age SD
Number of Males 11
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Day
Sampling Times Start Time: 08:00
End Time: 14:00
Number of Samples 3
Average Number of Samples Used for BV Estimation 3.0
Average Number of Replicates 2.0
Estimates of CVi 6.7
Calculated Confidence Intervals of CVi Lower: 4.74, Upper: 9.94
Estimates of CVg 83.9
Calculated Confidence Intervals of CVg Lower: 59.36, Upper: 142.57
Analytical CV 4.2
Calculated Confidence Intervals of Analytical CV Lower: 3.39, Upper: 5.53
Measurand Mean 17.3
Measurand Min
Measurand Max
Measurand SD