Alanine transaminase (ALT)

Reference

Reference
Bailey D, Bevilacqua V, Colantonio DA, Pasic MD, Perumal N, Chan MK and Adeli K, 2014, Clin Chem, 60, 518-29 , Pediatric within-day biological variation and quality spcifications for 38 biochemical markers in the CALIPER cohort

Scoring

Total Score

C10,13

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
11. ANOVA B
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C10,13
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Alanine transaminase (ALT)
Unit U / L
Overall Analytical Principle Method Dry chemistry
Number of Subjects 29
Number of Subjects included in BV estimation 29
Ethinicity Caucasian
Age Mean / Median
Age Min 4.0
Age Max 18.0
Age SD
Number of Males 16
Number of Females 13
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 1
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 4
Interval Units Day
Sampling Times Start Time: 09:30
End Time: 17:30
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 1.0
Estimates of CVi 15.6
Calculated Confidence Intervals of CVi Lower: 11.76, Upper: 18.85
Estimates of CVg 27.7
Calculated Confidence Intervals of CVg Lower: 21.42, Upper: 38.00
Analytical CV 7.0
Calculated Confidence Intervals of Analytical CV Lower: 4.96, Upper: 11.89
Measurand Mean 16.4
Measurand Min
Measurand Max
Measurand SD

Coding