EFLM Biological Varation Database : BIVAC Minimum Data Set for Alanine transaminase (ALT) EFLM Biological Variation

Alanine transaminase (ALT)

Reference

Bailey D, Bevilacqua V, Colantonio DA, Pasic MD, Perumal N, Chan MK and Adeli K, 2014, Clin Chem, 60, 518-29 , Pediatric within-day biological variation and quality spcifications for 38 biochemical markers in the CALIPER cohort

Scoring

Total Score

C_10,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	B
7. Steady State	B
8. Outlier Analysis	B
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	B
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_10,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Alanine transaminase (ALT)
Unit	U / L
Overall Analytical Principle Method	Dry VITROS DELETE
Number of Subjects	29
Number of Subjects included in BV estimation	29
Ethinicity	Caucasian
Age Mean / Median
Age Min	4.0
Age Max	18.0
Age SD
Number of Males	16
Number of Females	13
State of Well Being	Healthy (excl pregnant)
Study Duration Length	1
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	4
Interval Units	Day
Sampling Times	Start Time: 09:30 End Time: 17:30
Number of Samples	4
Average Number of Samples Used for BV Estimation	4.0
Average Number of Replicates	1.0
Estimates of CVi	15.6
Calculated Confidence Intervals of CVi	Lower: 11.76, Upper: 18.85
Estimates of CVg	27.7
Calculated Confidence Intervals of CVg	Lower: 21.42, Upper: 38.00
Analytical CV	7.0
Calculated Confidence Intervals of Analytical CV	Lower: 4.96, Upper: 11.89
Measurand Mean	16.4
Measurand Min
Measurand Max
Measurand SD

Coding

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