Alanine transaminase (ALT)


Pineda-Tenor D , Laserna-Mendieta EJ, Timon-Zapata J, Rodelgo-Jimenez L, Ramos-Corral R, Recio-Montealegre A and Gomez-Serranillos Reus M, 2013, Clin Chem Lab Med, 51, 851-62 , Biological variation and reference change value of common clinical chemistry and haematologic laboratory analytes in the eldery population


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,13

Item Details

Parameter Score
Matrix Serum
Measurand Alanine transaminase (ALT)
Unit micromol / L
Overall Analytical Principle Method Enzymatic analysis - IFCC method
Number of Subjects 64
Number of Subjects included in BV estimation 64
Ethinicity Caucasian
Age Mean / Median
Age Min 80.0
Age Max 89.0
Age SD
Number of Males
Number of Females 64
State of Well Being
Healthy (excl pregnant)
Study Duration Length 30
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08:00
End Time: 10:00
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 1.0
Estimates of CVi 23.9
Calculated Confidence Intervals of CVi Lower: 21.52, Upper: 26.72
Estimates of CVg 47.7
Calculated Confidence Intervals of CVg Lower: 40.15, Upper: 58.28
Analytical CV 6.1
Calculated Confidence Intervals of Analytical CV Lower: 4.78, Upper: 8.42
Measurand Mean 0.3
Measurand Min
Measurand Max
Measurand SD