Alanine transaminase (ALT)


Hölzel WGE, 1987, Clin Chem, 33, 57-61 , Intra-individual variation of some analytes in serum of patients with insulin-dependent diabetes mellitus


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand C
5. Pre-Analytical B
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C4,8,13
Comment * no information about PLP

Item Details

Parameter Score
Matrix Serum
Measurand Alanine transaminase (ALT)
Unit micromol / L
Overall Analytical Principle Method Enzymatic analysis - Not specified
Number of Subjects 16
Number of Subjects included in BV estimation 16
Ethinicity Caucasian
Age Mean / Median 38.7
Age Min 18.0
Age Max 52.0
Age SD
Number of Males 16
Number of Females
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 60 days
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 06:30
End Time: 08:00
Number of Samples 8
Average Number of Samples Used for BV Estimation 8.0
Average Number of Replicates 2.0
Estimates of CVi 13.0
Calculated Confidence Intervals of CVi Lower: 11.37, Upper: 15.09
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV 5.0
Calculated Confidence Intervals of Analytical CV Lower: 4.46, Upper: 5.70
Measurand Mean 0.523
Measurand Min
Measurand Max
Measurand SD