Aspartate transaminase (AST)

Included in meta analysis

Reference

Reference
Carobene A, Roraas T, Solvik UO, Sylte MS, Sandberg S, Guerra E, Marino I, Jonker N, Barla G, Barlett WA, Fernández-Calle P, Díaz-Garzón J, Tosato F, Plebani M, Coskun A, Serteser M, Unsal I and Ceriotti F, 2017, Clin Chem, 63, 1141-50 , Biological variation estimates obtained from 91 healthy study participants for 9 enzymes in serum

Scoring

Total Score

A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Aspartate transaminase (AST)
Unit U / L
Overall Analytical Principle Method Enzymatic analysis - IFCC method
Number of Subjects 53
Number of Subjects included in BV estimation 52
Ethinicity Caucasian
Age Mean / Median
Age Min 21.0
Age Max 69.0
Age SD
Number of Males
Number of Females 52
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 10 weeks
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08:00
End Time: 10:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 9.42
Average Number of Replicates 2.0
Estimates of CVi 8.9
Calculated Confidence Intervals of CVi Lower: 8.23, Upper: 9.65
Estimates of CVg 22.4
Calculated Confidence Intervals of CVg Lower: 18.72, Upper: 27.81
Analytical CV 5.5
Calculated Confidence Intervals of Analytical CV Lower: 5.17, Upper: 5.88
Measurand Mean 20.1
Measurand Min
Measurand Max
Measurand SD

Coding