EFLM Biological Varation Database : BIVAC Minimum Data Set for Aspartate transaminase (AST) EFLM Biological Variation

Aspartate transaminase (AST)

Reference

Pineda-Tenor D , Laserna-Mendieta EJ, Timon-Zapata J, Rodelgo-Jimenez L, Ramos-Corral R, Recio-Montealegre A and Gomez-Serranillos Reus M, 2013, Clin Chem Lab Med, 51, 851-62 , Biological variation and reference change value of common clinical chemistry and haematologic laboratory analytes in the eldery population

Originally from this reference: Clin Chem Lab Med, Pineda-Tenor D , Laserna-Mendieta EJ, Timon-Zapata J, Rodelgo-Jimenez L, Ramos-Corral R, Recio-Montealegre A and Gomez-Serranillos Reus M, 2013

ID: 0246

Scoring

Total Score

C_8,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	B
6. Replicate Analysis	B
7. Steady State	B
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	A
11. ANOVA	B
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_8,13
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Aspartate transaminase (AST)
Unit	micromol / L
Overall Analytical Principle Method	Enzymatic analysis - IFCC method
Number of Subjects	64
Number of Subjects included in BV estimation
Ethinicity	Caucasian
Age Mean / Median
Age Min	80.0
Age Max	89.0
Age SD
Number of Males
Number of Females	64
State of Well Being	Healthy (excl pregnant)
Study Duration Length	30
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Week
Sampling Times	Start Time: 08:00 End Time: 10:00
Number of Samples	4
Average Number of Samples Used for BV Estimation	4.0
Average Number of Replicates	1.0
Estimates of CVi	18.3
Calculated Confidence Intervals of CVi	Lower: 16.56, Upper: 20.41
Estimates of CVg	26.2
Calculated Confidence Intervals of CVg	Lower: 21.78, Upper: 32.30
Analytical CV	3.6
Calculated Confidence Intervals of Analytical CV	Lower: 2.82, Upper: 4.97
Measurand Mean	0.34
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	true
Adult Population	false
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Males
Snomed CT
NPU
LOINC
Comment	elderly

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