EFLM Biological Varation Database : BIVAC Minimum Data Set for Aspartate transaminase (AST) EFLM Biological Variation

Aspartate transaminase (AST)

Reference

Hölzel WGE, 1987, Clin Chem, 33, 57-61 , Intra-individual variation of some analytes in serum of patients with insulin-dependent diabetes mellitus

Originally from this reference: Clin Chem, Hölzel WGE, 1987

ID: 0072

Scoring

Total Score

C_4,8,13

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	C
5. Pre-Analytical	B
6. Replicate Analysis	A
7. Steady State	B
8. Outlier Analysis	C
9. Normality	A
10. Variance Homogeneity	A
11. ANOVA	B
12. CI	A
13. No of Results	C
14. Concentrations	A
15. Total Score	C_4,8,13
Comment	* no information about PLP

Item Details

Parameter	Score
Matrix	Serum
Measurand	Aspartate transaminase (AST)
Unit	micromol / L
Overall Analytical Principle Method	Enzymatic analysis - Not specified
Number of Subjects	16
Number of Subjects included in BV estimation	16
Ethinicity	Caucasian
Age Mean / Median	38.7
Age Min	18.0
Age Max	52.0
Age SD
Number of Males	16
Number of Females
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length	60
Study Duration Units	Day
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Week
Sampling Times	Start Time: 06:30 End Time: 08:00
Number of Samples	8
Average Number of Samples Used for BV Estimation	8.0
Average Number of Replicates	2.0
Estimates of CVi	12.3
Calculated Confidence Intervals of CVi	Lower: 10.74, Upper: 14.30
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: 0.00, Upper:
Analytical CV	5.0
Calculated Confidence Intervals of Analytical CV	Lower: 4.46, Upper: 5.70
Measurand Mean	0.483
Measurand Min
Measurand Max
Measurand SD

Coding

Parameter	Score
Healthy Population	false
Adult Population	true
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Males
Snomed CT
NPU
LOINC
Comment	IDMM

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