Haemoglobin A1c (NGSP)


Watts CF, Morris RW, Goodland FC, Kubal C and Shaw KM, 1989, Practical Diabetes, 6, 159-63 , Serum fructosamine and glycosylated haemoglobin in the monitoring of glycaemic control in insulin-dependent diabetic outpatients


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,10,11,12,13
Comment 1) Data may not be used for estimation of RCV (9B). 2) Data is not necessarily representative for the total population (10C).

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Haemoglobin A1c (NGSP)
Unit % / _
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 172
Number of Subjects included in BV estimation 172
Ethinicity Caucasian
Age Mean / Median 31.4
Age Min 12.0
Age Max 60.0
Age SD
Number of Males 96
Number of Females 76
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 21
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 7
Average Number of Samples Used for BV Estimation 7.0
Average Number of Replicates
Estimates of CVi 9.14
Calculated Confidence Intervals of CVi Lower: , Upper:
Estimates of CVg 20.24
Calculated Confidence Intervals of CVg Lower: 0.00, Upper:
Analytical CV
Calculated Confidence Intervals of Analytical CV Lower: , Upper:
Measurand Mean 10.72
Measurand Min
Measurand Max
Measurand SD