Shand B, Elder P, Scott R Frampton C and Willis J, 2006, Clin Chem Lab Med, 44, 1264-8 , Biovariabiity of plasma adiponectin


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,10,12,13
Comment C8,C10,C13

Item Details

Parameter Score
Matrix Plasma
Measurand Adiponectin
Unit ug / mL
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 10
Number of Subjects included in BV estimation 10
Ethinicity Unknown
Age Mean / Median 39.0
Age Min 28.0
Age Max 51.0
Age SD
Number of Males 5
Number of Females 5
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 30
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 10
Interval Units Day
Sampling Times Start Time: 08:00
End Time: 09:00
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 12.2
Calculated Confidence Intervals of CVi Lower: 8.02, Upper: 17.72
Estimates of CVg 38.6
Calculated Confidence Intervals of CVg Lower: 26.44, Upper: 68.53
Analytical CV 11.0
Calculated Confidence Intervals of Analytical CV Lower: 9.03, Upper: 14.07
Measurand Mean 3.7
Measurand Min
Measurand Max
Measurand SD