Included in meta analysis


Shand B, Elder P, Scott R Frampton C and Willis J, 2006, Clin Chem Lab Med, 44, 1264-8 , Biovariabiity of plasma adiponectin


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C8,10,12,13
Comment C8, C10, C13

Item Details

Parameter Score
Matrix Plasma
Measurand Adiponectin
Unit ug / mL
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 10
Number of Subjects included in BV estimation 10
Ethinicity Unknown
Age Mean / Median 38.0
Age Min 27.0
Age Max 49.0
Age SD
Number of Males 5
Number of Females 5
State of Well Being
Healthy (excl pregnant)
Study Duration Length 30
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 10
Interval Units Day
Sampling Times Start Time: 08:00
End Time: 09:00
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 18.8
Calculated Confidence Intervals of CVi Lower: 14.65, Upper: 25.56
Estimates of CVg 51.2
Calculated Confidence Intervals of CVg Lower: 35.05, Upper: 90.94
Analytical CV 7.5
Calculated Confidence Intervals of Analytical CV Lower: 6.16, Upper: 9.60
Measurand Mean 6.3
Measurand Min
Measurand Max
Measurand SD