Reference
Anna Carobene*, Elisabet Gonzalez Lao, Margarida Simon, Massimo Locatelli, Abdurrahman Coşkun, Jorge Díaz-Garzón, Pilar Fernandez-Calle, Sverre Sandberg and Aasne K. Aarsand, , 2020, Clin Chem Lab Med, 60, 518-522 , Biological variation of serum insulin: updated estimates from the European Biological Variation Study (EuBIVAS) and meta-analysis
Parameter | Score |
---|---|
1. Scale | A |
2. Study Population | A |
3. Samples | A |
4. Measurand | A |
5. Pre-Analytical | A |
6. Replicate Analysis | A |
7. Steady State | A |
8. Outlier Analysis | A |
9. Normality | A |
10. Variance Homogeneity | A |
11. ANOVA | A |
12. CI | A |
13. No of Results | A |
14. Concentrations | A |
15. Total Score | A1,2,3,4,5,6,7,8,9,10,11,12,13,14 |
Comment |
Parameter | Score |
---|---|
Matrix | Serum |
Measurand | Insulin |
Unit | microU / mL |
Overall Analytical Principle Method | Immunoassay; Other |
Number of Subjects | 91 |
Number of Subjects included in BV estimation | 90 |
Ethinicity | Caucasian |
Age Mean / Median | |
Age Min | 21.0 |
Age Max | 69.0 |
Age SD | |
Number of Males | 38 |
Number of Females | 53 |
State of Well Being |
Healthy (excl pregnant)
|
Diseases | |
Study Duration Length | 10 |
Study Duration Units | Week |
Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
Interval Units | Week |
Sampling Times | Start Time:
08.00
End Time: 10.00 |
Number of Samples | 10 |
Average Number of Samples Used for BV Estimation | 1.97 |
Average Number of Replicates | 2.0 |
Estimates of CVi | 25.3 |
Calculated Confidence Intervals of CVi | Lower: 22.01, Upper: 29.74 |
Estimates of CVg | 33.4 |
Calculated Confidence Intervals of CVg | Lower: 27.41, Upper: 40.70 |
Analytical CV | 3.1 |
Calculated Confidence Intervals of Analytical CV | Lower: 2.71, Upper: 3.63 |
Measurand Mean | 7.65 |
Measurand Min | 7.47 |
Measurand Max | 7.83 |
Measurand SD |