Corte Z, Venta R, 2020, Ann Transl Med, 8(6), 281-91 , Biological variation of metabolic cardiovascular risk factors in haemodialysis patients and healthy individuals


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Item Details

Parameter Score
Matrix Serum
Measurand Folate
Unit nmol / L
Overall Analytical Principle Method Immunoassay; Other
Number of Subjects 18
Number of Subjects included in BV estimation
Ethinicity Caucasian
Age Mean / Median
Age Min 31.0
Age Max 75.0
Age SD
Number of Males 7
Number of Females 11
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 6
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 8:30
End Time: 10:00
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 2.0
Estimates of CVi 13.0
Calculated Confidence Intervals of CVi Lower: 11.34, Upper: 15.23
Estimates of CVg 52.0
Calculated Confidence Intervals of CVg Lower: 39.13, Upper: 77.11
Analytical CV 1.0
Calculated Confidence Intervals of Analytical CV Lower: 0.88, Upper: 1.15
Measurand Mean 21.0
Measurand Min
Measurand Max
Measurand SD