Reference
Coşkun A, Aarsand AK, Sandberg S, Guerra E, Locatelli M, Díaz-Garzón J, Fernandez-Calle P, Ceriotti F, Jonker N, Bartlett WA, Carobene A, 2021, Clin Chem Lab Med, Online ahead of print, , Within- and between-subject biological variation data for tumor markers based on the European Biological Variation Study
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | A |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | A |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | A1,2,3,4,5,6,7,8,9,10,11,12,13,14 |
| Comment |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Cyfra21-1 |
| Unit | ug / L |
| Overall Analytical Principle Method | Immunoassay; Not specified |
| Number of Subjects | 37 |
| Number of Subjects included in BV estimation | 37 |
| Ethinicity | Caucasian |
| Age Mean / Median | |
| Age Min | 21.0 |
| Age Max | 69.0 |
| Age SD | |
| Number of Males | 37 |
| Number of Females | |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 10 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
08:00
End Time: 10:00 |
| Number of Samples | 10 |
| Average Number of Samples Used for BV Estimation | 10.0 |
| Average Number of Replicates | 2.0 |
| Estimates of CVi | 18.7 |
| Calculated Confidence Intervals of CVi | Lower: 17.37, Upper: 20.25 |
| Estimates of CVg | 29.9 |
| Calculated Confidence Intervals of CVg | Lower: 24.13, Upper: 38.99 |
| Analytical CV | 2.5 |
| Calculated Confidence Intervals of Analytical CV | Lower: 2.33, Upper: 2.69 |
| Measurand Mean | 1.53 |
| Measurand Min | 1.5 |
| Measurand Max | 1.6 |
| Measurand SD |