Included in meta analysis


Bal C, Erdogan S, Gök G, Nural C, Özbek B, Ercan M, Serdar M, Erel Ö, 2021 April, Turkish Journal of Biochemistry (TJB), Ahead of print, , Biological variation and reference change value data for serum copper, zinc and selenium in Turkish adult population


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C7,8

Item Details

Parameter Score
Matrix Serum
Measurand Zinc
Unit ug / dL
Overall Analytical Principle Method MS; ICP-MS
Number of Subjects 15
Number of Subjects included in BV estimation 13
Ethinicity Caucasian
Age Mean / Median
Age Min 20.0
Age Max 45.0
Age SD
Number of Males
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 09.00
End Time: 10.00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 9.1
Calculated Confidence Intervals of CVi Lower: 7.94, Upper: 10.57
Estimates of CVg 13.7
Calculated Confidence Intervals of CVg Lower: 9.70, Upper: 22.40
Analytical CV 4.2
Calculated Confidence Intervals of Analytical CV Lower: 3.75, Upper: 4.78
Measurand Mean 97.7
Measurand Min
Measurand Max
Measurand SD