Thyroid stimulating hormone (TSH)

Included in meta analysis

Reference

Reference
Bottani M, Aarsand AK, Banfi G, Locatelli M, Coşkun A, Díaz-Garzón J, Fernandez-Calle P, Sandberg S, Ceriotti F, Carobene A., 2021, Clin Chem Lab Med, Online ahead of print, Online ahead of print , European Biological Variation Study (EuBIVAS): within- and between-subject biological variation estimates for serum thyroid biomarkers based on weekly samplings from 91 healthy participants

Scoring

Total Score

A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Thyroid stimulating hormone (TSH)
Unit mIU / L
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 91
Number of Subjects included in BV estimation 85
Ethinicity Caucasian
Age Mean / Median
Age Min 21.0
Age Max 69.0
Age SD
Number of Males 38
Number of Females 53
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 8:00
End Time: 10:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 9.33
Average Number of Replicates 1.96
Estimates of CVi 17.7
Calculated Confidence Intervals of CVi Lower: 16.82, Upper: 18.68
Estimates of CVg 35.9
Calculated Confidence Intervals of CVg Lower: 31.09, Upper: 42.40
Analytical CV 1.46
Calculated Confidence Intervals of Analytical CV Lower: 1.39, Upper: 1.54
Measurand Mean 2.2
Measurand Min
Measurand Max
Measurand SD

Coding