Reference
Clouet-Foraison N, Marcovina SM, Guerra E, Aarsand AK, Coşkun A, Díaz-Garzón J, Fernandez-Calle P, Sandberg S, Ceriotti F, Carobene A., 2020, Clin Chem, 66, 727-36 , Analytical Performance Specifications for Lipoprotein(a), Apolipoprotein B-100, and Apolipoprotein A-I Using the Biological Variation Model in the EuBIVAS Population
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | A |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | A |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | A1,2,3,4,5,6,7,8,9,10,11,12,13,14, |
| Comment | A |
| Parameter | Score |
|---|---|
| Matrix | Serum |
| Measurand | Lipoprotein (a) |
| Unit | mmol / L |
| Overall Analytical Principle Method | Immunoturbidimetry |
| Number of Subjects | 91 |
| Number of Subjects included in BV estimation | 66 |
| Ethinicity | Caucasian |
| Age Mean / Median | |
| Age Min | 21.0 |
| Age Max | 69.0 |
| Age SD | |
| Number of Males | 38 |
| Number of Females | 53 |
| State of Well Being |
Healthy (excl pregnant)
|
| Diseases | |
| Study Duration Length | 10 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
End Time: |
| Number of Samples | 10 |
| Average Number of Samples Used for BV Estimation | 8.6 |
| Average Number of Replicates | 1.9 |
| Estimates of CVi | 8.9 |
| Calculated Confidence Intervals of CVi | Lower: 8.35, Upper: 9.52 |
| Estimates of CVg | |
| Calculated Confidence Intervals of CVg | Lower: , Upper: |
| Analytical CV | 3.1 |
| Calculated Confidence Intervals of Analytical CV | Lower: 2.91, Upper: 3.31 |
| Measurand Mean | 73.1 |
| Measurand Min | |
| Measurand Max | |
| Measurand SD |