Tumor necrosis factor (TNF)

Included in meta analysis


González C, Cava F, Ayllon A, Guevara P, Navajo JA, Gonzalez-Buitrago JM, 2001, Clin Chem Lab Med, 39(9), 836-413 , Biological variation of interleukin-1β, interleukin-8 and tumor necrosis factor-α in serum of healthy individuals


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
12. CI C
13. No of Results B
14. Concentrations A
15. Total Score C12

Item Details

Parameter Score
Matrix Serum
Measurand Tumor necrosis factor (TNF)
Unit pg / mL
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 15
Number of Subjects included in BV estimation 15
Ethinicity Unknown
Age Mean / Median
Age Min 25.0
Age Max 51.0
Age SD
Number of Males 4
Number of Females 11
State of Well Being
Healthy (excl pregnant)
Study Duration Length 6
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 8:00
End Time: 9:30
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 1.0
Estimates of CVi 43.0
Calculated Confidence Intervals of CVi Lower: 35.36, Upper: 51.85
Estimates of CVg 29.0
Calculated Confidence Intervals of CVg Lower: 16.93, Upper: 49.77
Analytical CV 12.9
Calculated Confidence Intervals of Analytical CV Lower: 8.87, Upper: 23.55
Measurand Mean 3.14
Measurand Min
Measurand Max
Measurand SD