Interleukin-6 (IL6)

Included in meta analysis


Cava F, Gonza ́lez C, Pascual MJ, Navajo JA, Gonza ́lez-Buitrago JM, 2000, CYTOKINE, 12(9), 1423–1425 , Biological variation of interleukin 6 (IL-6) and soluble interleukin 2 receptor (sIL2R) in serum of healthy individuals


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand B
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand Interleukin-6 (IL6)
Unit pg / mL
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 15
Number of Subjects included in BV estimation 15
Ethinicity Unknown
Age Mean / Median
Age Min 25.0
Age Max 51.0
Age SD
Number of Males 4
Number of Females 11
State of Well Being
Healthy (excl pregnant)
Study Duration Length 6
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 8:00
End Time: 9:30
Number of Samples 6
Average Number of Samples Used for BV Estimation 6.0
Average Number of Replicates 1.0
Estimates of CVi 48.48
Calculated Confidence Intervals of CVi Lower: 0.00, Upper: 81.44
Estimates of CVg 39.38
Calculated Confidence Intervals of CVg Lower: 12.39, Upper: 74.02
Analytical CV 76.1
Calculated Confidence Intervals of Analytical CV Lower: 52.34, Upper: 138.93
Measurand Mean 1.43
Measurand Min
Measurand Max
Measurand SD