25-hydroxy vitamin D3


Hofmann JN, Yu K, Horst RL, Hayes RB, Purdue MP, 2010, Cancer Epidemiol Biomarkers Prev, 19(4), 927-931. , Long-term Variation in Serum 25-Hydroxyvitamin D Concentration among Participants in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial


Total Score


Parameter Score
1. Scale A
2. Study Population B
3. Samples B
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis C
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations B
15. Total Score C6,8,10,11,13

Item Details

Parameter Score
Matrix Serum
Measurand 25-hydroxy vitamin D3
Unit nmol / L
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 28
Number of Subjects included in BV estimation 26
Ethinicity Caucasian
Age Mean / Median 61.0
Age Min 55.0
Age Max 70.0
Age SD
Number of Males 18
Number of Females 10
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 5
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Other
Sampling Times Start Time:
End Time:
Number of Samples 3
Average Number of Samples Used for BV Estimation 3.0
Average Number of Replicates 1.0
Estimates of CVi 14.9
Calculated Confidence Intervals of CVi Lower: , Upper:
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV
Calculated Confidence Intervals of Analytical CV Lower: , Upper:
Measurand Mean
Measurand Min
Measurand Max
Measurand SD