25-hydroxy vitamin D3

Included in meta analysis


Brescia V, Tampoia M, Cardinali R, 2013, Lab Med, 44(1), 20–24 , Biological Variability of Serum 25-Hydroxyvitamin D and Other Biomarkers in Healthy Subjects


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C8,10

Item Details

Parameter Score
Matrix Serum
Measurand 25-hydroxy vitamin D3
Unit ug / mL
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 11
Number of Subjects included in BV estimation 11
Ethinicity Unknown
Age Mean / Median 46.0
Age Min 39.0
Age Max 55.0
Age SD
Number of Males 5
Number of Females 6
State of Well Being
Healthy (excl pregnant)
Study Duration Length 8
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08:30
End Time: 9:30
Number of Samples 8
Average Number of Samples Used for BV Estimation 8.0
Average Number of Replicates 2.0
Estimates of CVi 47.0
Calculated Confidence Intervals of CVi Lower: 40.56, Upper: 55.86
Estimates of CVg 64.3
Calculated Confidence Intervals of CVg Lower: 43.93, Upper: 111.52
Analytical CV 5.5
Calculated Confidence Intervals of Analytical CV Lower: 4.79, Upper: 6.45
Measurand Mean 24.3
Measurand Min
Measurand Max
Measurand SD