25-hydroxy vitamin D3

Included in meta analysis


Cokluk E, Akbay HI, Alp HH, 2021, Clin Lab, 67(9), , Biological Variation of Iron, Transferrin, Ferritin, Folate, Vitamin B12 and 25-OH Vitamin D in Healthy Individuals


Total Score


Parameter Score
1. Scale B
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score B1,6

Item Details

Parameter Score
Matrix Serum
Measurand 25-hydroxy vitamin D3
Unit ug / ug
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 21
Number of Subjects included in BV estimation 21
Ethinicity Unknown
Age Mean / Median
Age Min 18.0
Age Max 50.0
Age SD
Number of Males 10
Number of Females 11
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 7
Interval Units Day
Sampling Times Start Time: 08:30
End Time: 10:00
Number of Samples 5
Average Number of Samples Used for BV Estimation 4.48
Average Number of Replicates 2.0
Estimates of CVi 8.21
Calculated Confidence Intervals of CVi Lower: 6.95, Upper: 9.93
Estimates of CVg 54.9
Calculated Confidence Intervals of CVg Lower: 42.16, Upper: 78.56
Analytical CV 3.44
Calculated Confidence Intervals of Analytical CV Lower: 2.99, Upper: 4.05
Measurand Mean 188.0
Measurand Min
Measurand Max
Measurand SD