Cheuvront SN, Ely BR, Kenefick RW and Sawka MN, 2010, Am J Clin Nutr, 92, 565-73 , Biological variation and diagnostic accuracy of dehydration assessment markers


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis B
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C7

Item Details

Parameter Score
Matrix Morning urine
Measurand Osmolality
Unit mmol / Kg
Overall Analytical Principle Method Freezing point depression
Number of Subjects 18
Number of Subjects included in BV estimation 18
Ethinicity Unknown
Age Mean / Median 24.0
Age Min
Age Max
Age SD 4.0
Number of Males 13
Number of Females 5
State of Well Being
Healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time: 6:30
End Time:
Number of Samples 3
Average Number of Samples Used for BV Estimation 3.0
Average Number of Replicates 3.0
Estimates of CVi 28.3
Calculated Confidence Intervals of CVi Lower: 23.01, Upper: 36.76
Estimates of CVg 57.9
Calculated Confidence Intervals of CVg Lower: 42.30, Upper: 87.43
Analytical CV 0.7
Calculated Confidence Intervals of Analytical CV Lower: 0.62, Upper: 0.81
Measurand Mean 614.0
Measurand Min
Measurand Max
Measurand SD 205.0