Included in meta analysis


Montagnana M, Paleari R, Danese E, Salvagno GL, Lippi G, Guidi GC and Mosca A, 2013, Clin Chim Acta, 423, 1-4 , Evaluation of biological variation of glycated albumin (GA) and fructosamine in healthy subjects


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13

Item Details

Parameter Score
Matrix Plasma
Measurand Albumin
Unit g / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 18
Number of Subjects included in BV estimation 18
Ethinicity Caucasian
Age Mean / Median
Age Min 26.0
Age Max 52.0
Age SD
Number of Males 9
Number of Females 9
State of Well Being
Healthy (excl pregnant)
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 14
Interval Units Day
Sampling Times Start Time: 9:00
End Time: 9:30
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 2.3
Calculated Confidence Intervals of CVi Lower: 1.73, Upper: 2.96
Estimates of CVg 2.9
Calculated Confidence Intervals of CVg Lower: 2.01, Upper: 4.50
Analytical CV 2.3
Calculated Confidence Intervals of Analytical CV Lower: 2.01, Upper: 2.69
Measurand Mean 46.3
Measurand Min
Measurand Max
Measurand SD