Alkaline phosphatase (ALP), liver type


Pagani F and Panteghini M, 2001, Clin Chem, 47, 355-6 , Biological variation in serum activities of three hepatic enzymes


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,10,13,
Comment C

Item Details

Parameter Score
Matrix Serum
Measurand Alkaline phosphatase (ALP), liver type
Unit U / L
Overall Analytical Principle Method Enzymatic analysis - IFCC method
Number of Subjects 5
Number of Subjects included in BV estimation 5
Ethinicity Caucasian
Age Mean / Median
Age Min 25.0
Age Max 50.0
Age SD
Number of Males 5
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 30
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08
End Time: 09:00
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 6.4
Calculated Confidence Intervals of CVi Lower: 4.65, Upper: 10.02
Estimates of CVg 23.0
Calculated Confidence Intervals of CVg Lower: 14.12, Upper: 56.88
Analytical CV 1.8
Calculated Confidence Intervals of Analytical CV Lower: 1.38, Upper: 2.60
Measurand Mean 57.0
Measurand Min
Measurand Max
Measurand SD