Biosca C, Ricós C, Jiménez CV, Lauzurica R and Galimany R, 1997, Clin Chem, 43, 2206-8 , Model for establishing biological variation in non-healthy situations: renal posttranplantation data


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations B
15. Total Score C10

Item Details

Parameter Score
Matrix Serum
Measurand Urate
Unit mmol / L
Overall Analytical Principle Method Unknown
Number of Subjects 19
Number of Subjects included in BV estimation 19
Ethinicity Caucasian
Age Mean / Median
Age Min 19.0
Age Max 64.0
Age SD
Number of Males 12
Number of Females 7
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 48
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 16
Interval Units Year
Sampling Times Start Time: unknown
End Time: unknown
Number of Samples 33
Average Number of Samples Used for BV Estimation 33.0
Average Number of Replicates 1.0
Estimates of CVi 12.3
Calculated Confidence Intervals of CVi Lower: 11.55, Upper: 13.11
Estimates of CVg 11.7
Calculated Confidence Intervals of CVg Lower: 8.78, Upper: 17.25
Analytical CV 3.8
Calculated Confidence Intervals of Analytical CV Lower: 3.23, Upper: 4.61
Measurand Mean
Measurand Min
Measurand Max
Measurand SD