Actual bicarbonate

Included in meta analysis


Harding PJ, Fraser CG, 1987, Clin Chem , 33, 1416-8 , Biological variation of blood acid-base status: consequences for analytical goal-setting and interpretation of results


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C7,8,10

Item Details

Parameter Score
Matrix Whole blood
Measurand Actual bicarbonate
Unit mmol / L
Overall Analytical Principle Method Spectrophotometry; Other
Number of Subjects 14
Number of Subjects included in BV estimation 14
Ethinicity Caucasian
Age Mean / Median
Age Min 20.0
Age Max 42.0
Age SD
Number of Males 9
Number of Females 5
State of Well Being
Healthy (excl pregnant)
Study Duration Length 14
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 11:00
End Time: 14:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 4.0
Calculated Confidence Intervals of CVi Lower: 3.38, Upper: 4.74
Estimates of CVg 4.8
Calculated Confidence Intervals of CVg Lower: 3.37, Upper: 7.77
Analytical CV 3.2
Calculated Confidence Intervals of Analytical CV Lower: 2.87, Upper: 3.62
Measurand Mean 24.5
Measurand Min
Measurand Max
Measurand SD