Pineda-Tenor D , Laserna-Mendieta EJ, Timon-Zapata J, Rodelgo-Jimenez L, Ramos-Corral R, Recio-Montealegre A and Gomez-Serranillos Reus M, 2013, Clin Chem Lab Med, 51, 851-62 , Biological variation and reference change value of common clinical chemistry and haematologic laboratory analytes in the eldery population


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity A
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C8,13

Item Details

Parameter Score
Matrix Serum
Measurand Phosphate
Unit mmol / L
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 71
Number of Subjects included in BV estimation 65
Ethinicity Unknown
Age Mean / Median 80.0
Age Min
Age Max
Age SD
Number of Males 71
Number of Females 0
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 8
End Time: 10
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 1.0
Estimates of CVi 8.1
Calculated Confidence Intervals of CVi Lower: 7.23, Upper: 9.08
Estimates of CVg 8.7
Calculated Confidence Intervals of CVg Lower: 7.07, Upper: 10.89
Analytical CV 2.6
Calculated Confidence Intervals of Analytical CV Lower: 2.05, Upper: 3.56
Measurand Mean 1.0
Measurand Min
Measurand Max
Measurand SD