Haemoglobin A1c (NGSP)

Reference

Reference
Ucar F, Erden G, Ginis Z, Ozturk G, Szser S, Gurler M and Guneyk A, 2013, Clin Biochem, 46, 1548-53 , Estimation of biological variation and reference change value of glycated hemoglobin (HbA1c) when two analytical methods are used

Scoring

Total Score

C10

Parameter Score
1. Scale B
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis A
9. Normality B
10. Variance Homogeneity C
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C10
Comment

Item Details

Parameter Score
Matrix Whole Blood EDTA
Measurand Haemoglobin A1c (NGSP)
Unit % / _
Overall Analytical Principle Method Chromatography; HPLC
Number of Subjects 9
Number of Subjects included in BV estimation 9
Ethinicity Unknown
Age Mean / Median
Age Min 20.0
Age Max 45.0
Age SD
Number of Males 0
Number of Females 9
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 3
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 1.23
Calculated Confidence Intervals of CVi Lower: 0.24, Upper: 2.01
Estimates of CVg 5.75
Calculated Confidence Intervals of CVg Lower: 3.90, Upper: 10.58
Analytical CV 1.68
Calculated Confidence Intervals of Analytical CV Lower: 1.37, Upper: 2.18
Measurand Mean 5.37
Measurand Min
Measurand Max
Measurand SD

Coding