D-dimer level

Included in meta analysis

Reference

Reference
Kristoffersen AH, Petersen PH and Sandberg S, 2012, Ann Clin Biochem, 49, 561-9 , A model for calculating the within-subject biological variation and likelihood ratios for analytes with a time-dependent change in concentrations; exemplified with the use of D-dimer in suspected venous thromboembolism in healthy pregnant women

Scoring

Total Score

A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14
Comment

Item Details

Parameter Score
Matrix Plasma
Measurand D-dimer level
Unit mg / L (FEU)
Overall Analytical Principle Method Immunoturbidimetry
Number of Subjects 19
Number of Subjects included in BV estimation 18
Ethinicity Caucasian
Age Mean / Median 33.5
Age Min 23.0
Age Max 40.0
Age SD
Number of Males 0
Number of Females 19
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 40
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 8:00
End Time: 13:30
Number of Samples 10
Average Number of Samples Used for BV Estimation 9.4
Average Number of Replicates 2.0
Estimates of CVi 23.3
Calculated Confidence Intervals of CVi Lower: 17.40, Upper: 29.00
Estimates of CVg 26.5
Calculated Confidence Intervals of CVg Lower: 18.73, Upper: 40.83
Analytical CV 31.8
Calculated Confidence Intervals of Analytical CV Lower: 28.68, Upper: 35.68
Measurand Mean
Measurand Min
Measurand Max
Measurand SD

Coding