Methylmalonate level

Reference

Reference
Lacher DA, Hughes JP and Carroll MD, 2010, National Health Statistics Reports , 21, , Biological variation of laboratory analytes based on the 1999–2002 National Health and Nutrition Examination Survey

Scoring

Total Score

C5,7,10

Parameter Score
1. Scale A
2. Study Population B
3. Samples A
4. Measurand A
5. Pre-Analytical C
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis A
9. Normality B
10. Variance Homogeneity C
11. ANOVA B
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C5,7,10
Comment

Item Details

Parameter Score
Matrix Plasma
Measurand Methylmalonate level
Unit micromol / L
Overall Analytical Principle Method MS; GC-MS
Number of Subjects 396
Number of Subjects included in BV estimation 396
Ethinicity Hispanic or Latino
Age Mean / Median
Age Min 16.0
Age Max 69.0
Age SD
Number of Males 396
Number of Females
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 36
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Other
Sampling Times Start Time:
End Time:
Number of Samples 2
Average Number of Samples Used for BV Estimation 2.0
Average Number of Replicates 1.0
Estimates of CVi 17.3
Calculated Confidence Intervals of CVi Lower: 15.86, Upper: 18.84
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 7.4
Calculated Confidence Intervals of Analytical CV Lower: 6.40, Upper: 8.77
Measurand Mean 0.14
Measurand Min
Measurand Max
Measurand SD

Coding