Thyroid stimulating hormone (TSH)


Jesper Karmisholt, Stig Andersen, Peter Laurberg, 2010 Jul, Scand J Clin Lab Invest, 70(4), 264-8 , Analytical Goals for Thyroid Function Tests When Monitoring Patients With Untreated Subclinical Hypothyroidism


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C8,10

Item Details

Parameter Score
Matrix Serum
Measurand Thyroid stimulating hormone (TSH)
Unit mIU / L
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 15
Number of Subjects included in BV estimation 15
Ethinicity Caucasian
Age Mean / Median 58.0
Age Min
Age Max
Age SD 13.0
Number of Males 2
Number of Females 13
State of Well Being
Non-healthy (excl pregnant)
Study Duration Length 13
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time: 09:00
End Time: 12:00
Number of Samples 13
Average Number of Samples Used for BV Estimation 13.0
Average Number of Replicates 2.0
Estimates of CVi 16.6
Calculated Confidence Intervals of CVi Lower: 15.04, Upper: 18.52
Estimates of CVg 23.2
Calculated Confidence Intervals of CVg Lower: 16.85, Upper: 36.32
Analytical CV 1.7
Calculated Confidence Intervals of Analytical CV Lower: 1.55, Upper: 1.89
Measurand Mean
Measurand Min
Measurand Max
Measurand SD