Troponin I, cardiac - high-sensitive (biweekly-monthly sampling)

Reference

Reference
Ceriotti F, Diaz-Garzon J et al, 2020, Clin Chem Lab Med, , , The European Biological Variation Study (EuBIVAS): weekly biological variation of cardiac troponin I estimated by the use of two different high-sensitivity cardiac troponin I assays

Scoring

Total Score

A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14
Comment SINGULEX CLARITY hs-TnI. Results > LoD

Item Details

Parameter Score
Matrix Serum
Measurand Troponin I, cardiac - high-sensitive (biweekly-monthly sampling)
Unit ng / L
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 89
Number of Subjects included in BV estimation 89
Ethinicity Caucasian
Age Mean / Median 35.0
Age Min 22.0
Age Max 59.0
Age SD
Number of Males 37
Number of Females 52
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 10
Average Number of Samples Used for BV Estimation
Average Number of Replicates
Estimates of CVi 16.6
Calculated Confidence Intervals of CVi Lower: 14.76, Upper: 18.09
Estimates of CVg 40.3
Calculated Confidence Intervals of CVg Lower: 35.01, Upper: 47.39
Analytical CV 11.6
Calculated Confidence Intervals of Analytical CV Lower: 10.12, Upper: 13.60
Measurand Mean 0.78
Measurand Min 0.75
Measurand Max 0.82
Measurand SD

Coding