Reference
Jones RA, Barratt J, Brettell EA, Cockwell P, Dalton RN, Deeks JJ, Eaglestone G, Pellatt-Higgins T, Kalra PA, Khunti K, Morris FS, Ottridge RS, Sitch AJ, Stevens PE, Sharpe CC, Sutton AJ, Taal MW, Lamb EJ, 2020, Ann Clin Biochem, , 4563220906431 , Biological variation of cardiac troponins in chronic kidney disease.
| Parameter | Score |
|---|---|
| 1. Scale | A |
| 2. Study Population | A |
| 3. Samples | A |
| 4. Measurand | A |
| 5. Pre-Analytical | A |
| 6. Replicate Analysis | A |
| 7. Steady State | B |
| 8. Outlier Analysis | A |
| 9. Normality | A |
| 10. Variance Homogeneity | A |
| 11. ANOVA | A |
| 12. CI | A |
| 13. No of Results | A |
| 14. Concentrations | A |
| 15. Total Score | B7 |
| Comment | moderate Kidney Disease. Results <LoD excluded. Roche |
| Parameter | Score |
|---|---|
| Matrix | Plasma |
| Measurand | Troponin T, cardiac - high-sensitive (biweekly-monthly sampling) |
| Unit | ng / L |
| Overall Analytical Principle Method | Immunoassay; Not specified |
| Number of Subjects | 20 |
| Number of Subjects included in BV estimation | 10 |
| Ethinicity | Caucasian |
| Age Mean / Median | 71.0 |
| Age Min | 50.0 |
| Age Max | 80.0 |
| Age SD | |
| Number of Males | 10 |
| Number of Females | 10 |
| State of Well Being |
Non-healthy (excl pregnant)
|
| Diseases |
|
| Study Duration Length | 4 |
| Study Duration Units | Week |
| Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
| Interval Units | Week |
| Sampling Times | Start Time:
End Time: |
| Number of Samples | 4 |
| Average Number of Samples Used for BV Estimation | 4.0 |
| Average Number of Replicates | 3.0 |
| Estimates of CVi | 7.4 |
| Calculated Confidence Intervals of CVi | Lower: 5.81, Upper: 10.02 |
| Estimates of CVg | 78.4 |
| Calculated Confidence Intervals of CVg | Lower: 54.71, Upper: 137.70 |
| Analytical CV | 3.1 |
| Calculated Confidence Intervals of Analytical CV | Lower: 2.69, Upper: 3.67 |
| Measurand Mean | 11.8 |
| Measurand Min | 4.9 |
| Measurand Max | 39.6 |
| Measurand SD |