Reference
Jones RA, Barratt J, Brettell EA, Cockwell P, Dalton RN, Deeks JJ, Eaglestone G, Pellatt-Higgins T, Kalra PA, Khunti K, Morris FS, Ottridge RS, Sitch AJ, Stevens PE, Sharpe CC, Sutton AJ, Taal MW, Lamb EJ, 2020, Ann Clin Biochem, , 4563220906431 , Biological variation of cardiac troponins in chronic kidney disease.
Parameter | Score |
---|---|
1. Scale | A |
2. Study Population | A |
3. Samples | A |
4. Measurand | A |
5. Pre-Analytical | A |
6. Replicate Analysis | A |
7. Steady State | B |
8. Outlier Analysis | A |
9. Normality | A |
10. Variance Homogeneity | A |
11. ANOVA | A |
12. CI | A |
13. No of Results | A |
14. Concentrations | A |
15. Total Score | B7 |
Comment | moderate Kidney Disease. Results <LoD excluded. Roche |
Parameter | Score |
---|---|
Matrix | Plasma |
Measurand | Troponin T, cardiac - high-sensitive (biweekly-monthly sampling) |
Unit | ng / L |
Overall Analytical Principle Method | Immunoassay; Not specified |
Number of Subjects | 20 |
Number of Subjects included in BV estimation | 10 |
Ethinicity | Caucasian |
Age Mean / Median | 71.0 |
Age Min | 50.0 |
Age Max | 80.0 |
Age SD | |
Number of Males | 10 |
Number of Females | 10 |
State of Well Being |
Non-healthy (excl pregnant)
|
Diseases |
|
Study Duration Length | 4 |
Study Duration Units | Week |
Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
Interval Units | Week |
Sampling Times | Start Time:
End Time: |
Number of Samples | 4 |
Average Number of Samples Used for BV Estimation | 4.0 |
Average Number of Replicates | 3.0 |
Estimates of CVi | 7.4 |
Calculated Confidence Intervals of CVi | Lower: 5.81, Upper: 10.02 |
Estimates of CVg | 78.4 |
Calculated Confidence Intervals of CVg | Lower: 54.71, Upper: 137.70 |
Analytical CV | 3.1 |
Calculated Confidence Intervals of Analytical CV | Lower: 2.69, Upper: 3.67 |
Measurand Mean | 11.8 |
Measurand Min | 4.9 |
Measurand Max | 39.6 |
Measurand SD |