Troponin I, cardiac - high-sensitive (biweekly-monthly sampling)


Jones RA, Barratt J, Brettell EA, Cockwell P, Dalton RN, Deeks JJ, Eaglestone G, Pellatt-Higgins T, Kalra PA, Khunti K, Morris FS, Ottridge RS, Sitch AJ, Stevens PE, Sharpe CC, Sutton AJ, Taal MW, Lamb EJ, 2020, Ann Clin Biochem, , 4563220906431 , Biological variation of cardiac troponins in chronic kidney disease.


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State B
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score B7
Comment moderate Kidney Disease. Results <LoD excluded. Abbott

Item Details

Parameter Score
Matrix Plasma
Measurand Troponin I, cardiac - high-sensitive (biweekly-monthly sampling)
Unit ng / L
Overall Analytical Principle Method Immunoassay; Not specified
Number of Subjects 20
Number of Subjects included in BV estimation 10
Ethinicity Caucasian
Age Mean / Median 71.0
Age Min 50.0
Age Max 80.0
Age SD
Number of Males 10
Number of Females 10
State of Well Being
Non-healthy (excl pregnant)
  • Renal failure
Study Duration Length 4
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 3.0
Estimates of CVi 15.0
Calculated Confidence Intervals of CVi Lower: 11.61, Upper: 20.49
Estimates of CVg 105.6
Calculated Confidence Intervals of CVg Lower: 73.57, Upper: 185.67
Analytical CV 8.3
Calculated Confidence Intervals of Analytical CV Lower: 7.19, Upper: 9.82
Measurand Mean 4.3
Measurand Min 1.3
Measurand Max 16.3
Measurand SD