Haemoglobin A1c (NGSP)


Lacher DA, Hughes JP and Carroll MD, 2005, Clin Chem, 51, 450-2 , Estimate of biological variation of laboratory analytes based on the third National Health and Nutrition Examination Survey


Total Score


Parameter Score
1. Scale B
2. Study Population B
3. Samples B
4. Measurand B
5. Pre-Analytical C
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C5,7,8,10,12,13

Item Details

Parameter Score
Matrix Whole blood
Measurand Haemoglobin A1c (NGSP)
Unit % / _
Overall Analytical Principle Method Unknown
Number of Subjects 2195
Number of Subjects included in BV estimation 2195
Ethinicity Unknown
Age Mean / Median 30.8
Age Min
Age Max
Age SD
Number of Males
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 6
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Other
Sampling Times Start Time:
End Time:
Number of Samples
Average Number of Samples Used for BV Estimation 2.0
Average Number of Replicates 1.0
Estimates of CVi 1.5
Calculated Confidence Intervals of CVi Lower: 0.48, Upper: 2.32
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 3.1
Calculated Confidence Intervals of Analytical CV Lower: 2.91, Upper: 3.32
Measurand Mean 5.34
Measurand Min
Measurand Max
Measurand SD