Widjaja A, Morris RJ, Levy JC, Frayn KN, Manley SE and Turner RC, 1999, Clin Chem , 45, 561-6 , Within- and between-subject variationin comoly measured anthropometricand biochemical variables.


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C8,10

Item Details

Parameter Score
Matrix Plasma
Measurand 3-hydroxybutyrate
Unit umol / L
Overall Analytical Principle Method Spectrophotometry; Enzymatic
Number of Subjects 12
Number of Subjects included in BV estimation 12
Ethinicity Mixed
Age Mean / Median 22.7
Age Min
Age Max
Age SD 1.5
Number of Males 6
Number of Females 6
State of Well Being
Healthy (excl pregnant)
Study Duration Length 12
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time: 8:00
End Time:
Number of Samples 12
Average Number of Samples Used for BV Estimation 12.0
Average Number of Replicates 1.0
Estimates of CVi 61.0
Calculated Confidence Intervals of CVi Lower: 54.39, Upper: 69.44
Estimates of CVg 41.0
Calculated Confidence Intervals of CVg Lower: 26.55, Upper: 71.53
Analytical CV 6.1
Calculated Confidence Intervals of Analytical CV Lower: 4.47, Upper: 9.62
Measurand Mean 42.5
Measurand Min
Measurand Max
Measurand SD