Cancer antigen 125 (CA-125)

Included in meta analysis


Tuxen MK, Solétormos G, Pertersen PH, Cioler V, Dombernovsky P, 1999, Gynecologic Oncology, 74, 12-22 , Assessment of biological variation and analytic impreciion of CA 125, CEA and TPA in relation to monitoring of ovarian cancer


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C10

Item Details

Parameter Score
Matrix Serum
Measurand Cancer antigen 125 (CA-125)
Unit U / mL
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 31
Number of Subjects included in BV estimation 31
Ethinicity Unknown
Age Mean / Median 55.0
Age Min 32.0
Age Max 71.0
Age SD
Number of Males
Number of Females 31
State of Well Being
Healthy (excl pregnant)
Study Duration Length 1
Study Duration Units Year
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Month
Sampling Times Start Time:
End Time:
Number of Samples 16
Average Number of Samples Used for BV Estimation 16.0
Average Number of Replicates 1.0
Estimates of CVi 23.3
Calculated Confidence Intervals of CVi Lower: 21.62, Upper: 25.10
Estimates of CVg 70.6
Calculated Confidence Intervals of CVg Lower: 56.48, Upper: 94.01
Analytical CV 7.8
Calculated Confidence Intervals of Analytical CV Lower: 6.52, Upper: 9.72
Measurand Mean 19.5
Measurand Min
Measurand Max
Measurand SD