C-reactive protein (CRP) - high-sensitive


Qi Z, Chen Y, Zhang L, Ma X, Wang F, Cheng Q, Du J, Hao Y, Chi S, Cui W, 2016, Clin Chim Acta, 452, 87-91 , Biological variations of thirteen plasma biochemical indicators


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand C-reactive protein (CRP) - high-sensitive
Unit mg / L
Overall Analytical Principle Method Immunoturbidimetry
Number of Subjects 21
Number of Subjects included in BV estimation 21
Ethinicity Asian
Age Mean / Median
Age Min 21.0
Age Max 68.0
Age SD
Number of Males 21
Number of Females
State of Well Being
Healthy (excl pregnant)
Study Duration Length 5
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Day
Sampling Times Start Time: 8:00
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates 2.0
Estimates of CVi 26.87
Calculated Confidence Intervals of CVi Lower: 23.34, Upper: 31.66
Estimates of CVg 37.91
Calculated Confidence Intervals of CVg Lower: 28.07, Upper: 55.54
Analytical CV 1.63
Calculated Confidence Intervals of Analytical CV Lower: 1.44, Upper: 1.88
Measurand Mean 0.4
Measurand Min
Measurand Max
Measurand SD