C-reactive protein (CRP)


Cho LW, Jayagopal V, Kilpatrick ES and Atkin SL, 2005, Clin Chem, 51, 1905-7 , The biological variation of C-reactive protein in polycystic ovarian syndrome


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results C
14. Concentrations A
15. Total Score C7,8,10,13

Item Details

Parameter Score
Matrix Serum
Measurand C-reactive protein (CRP)
Unit mg / L
Overall Analytical Principle Method Immunoturbidimetry
Number of Subjects 11
Number of Subjects included in BV estimation 11
Ethinicity Caucasian
Age Mean / Median 30.0
Age Min 19.0
Age Max 33.0
Age SD
Number of Males
Number of Females 11
State of Well Being
Healthy (excl pregnant)
Study Duration Length 2
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08:00
End Time: 09:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 10.0
Average Number of Replicates 2.0
Estimates of CVi 36.8
Calculated Confidence Intervals of CVi Lower: 32.31, Upper: 42.75
Estimates of CVg 62.2
Calculated Confidence Intervals of CVg Lower: 43.27, Upper: 106.80
Analytical CV 1.0
Calculated Confidence Intervals of Analytical CV Lower: 0.88, Upper: 1.15
Measurand Mean 1.07
Measurand Min
Measurand Max
Measurand SD