a-1 antitrypsin


Franzini C, Scapellato G and Vanoni G, 1993, Biochim Clin, 17, 315-9 , Variabilità bologica ed analitica della anti-streptolisina O e di proteine della fase acuta del siero


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State C
8. Outlier Analysis B
9. Normality B
10. Variance Homogeneity C
12. CI A
13. No of Results B
14. Concentrations B
15. Total Score C7,10

Item Details

Parameter Score
Matrix Serum
Measurand a-1 antitrypsin
Unit mg / dL
Overall Analytical Principle Method Immunoturbidimetry
Number of Subjects 12
Number of Subjects included in BV estimation 10
Ethinicity Unknown
Age Mean / Median
Age Min 22.0
Age Max 42.0
Age SD
Number of Males 4
Number of Females 8
State of Well Being
Healthy (excl pregnant)
Study Duration Length 21
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 3
Interval Units Week
Sampling Times Start Time: 08:00
End Time: 09:00
Number of Samples 8
Average Number of Samples Used for BV Estimation 7.5
Average Number of Replicates 2.0
Estimates of CVi 4.8
Calculated Confidence Intervals of CVi Lower: 3.90, Upper: 5.99
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: , Upper:
Analytical CV 3.1
Calculated Confidence Intervals of Analytical CV Lower: 2.66, Upper: 3.71
Measurand Mean
Measurand Min
Measurand Max
Measurand SD