a-1 antitrypsin

Reference

Reference
Bailey D, Bevilacqua V, Colantonio DA, Pasic MD, Perumal N, Chan MK and Adeli K, 2014, Clin Chem, 60, 518-29 , Pediatric within-day biological variation and quality spcifications for 38 biochemical markers in the CALIPER cohort

Scoring

Total Score

C10,12

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis B
9. Normality A
10. Variance Homogeneity C
11. ANOVA A
12. CI C
13. No of Results B
14. Concentrations A
15. Total Score C10,12
Comment

Item Details

Parameter Score
Matrix Plasma
Measurand a-1 antitrypsin
Unit mg / dL
Overall Analytical Principle Method Turbidimetry
Number of Subjects 29
Number of Subjects included in BV estimation 14
Ethinicity Unknown
Age Mean / Median
Age Min 15.0
Age Max 19.0
Age SD
Number of Males 13
Number of Females 16
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 1
Study Duration Units Day
Sampling Intervals, e.g. X sample(s) per Interval Unit 2
Interval Units Hour
Sampling Times Start Time: 09:30
End Time: 17:30
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 1.0
Estimates of CVi 5.0
Calculated Confidence Intervals of CVi Lower: 2.94, Upper: 6.51
Estimates of CVg 13.0
Calculated Confidence Intervals of CVg Lower: 9.34, Upper: 20.75
Analytical CV 1.8
Calculated Confidence Intervals of Analytical CV Lower: 1.12, Upper: 4.41
Measurand Mean 120.0
Measurand Min
Measurand Max
Measurand SD

Coding