C-reactive protein (CRP)


Carobene A, Aarsand AK, Guerra E et al, 2019, Clin Chem, 65 (8), 1031-41 , Within- and Between-Subject Biological Variation Data for 15 Frequently Measured Proteins


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Item Details

Parameter Score
Matrix Serum
Measurand C-reactive protein (CRP)
Unit mg / L
Overall Analytical Principle Method Immunoturbidimetry
Number of Subjects 53
Number of Subjects included in BV estimation 50
Ethinicity Caucasian
Age Mean / Median
Age Min 21.0
Age Max 69.0
Age SD
Number of Males
Number of Females 53
State of Well Being
Healthy (excl pregnant)
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time: 08:00
End Time: 10:00
Number of Samples 10
Average Number of Samples Used for BV Estimation 8.34
Average Number of Replicates 1.93
Estimates of CVi 29.9
Calculated Confidence Intervals of CVi Lower: 27.73, Upper: 32.40
Estimates of CVg 80.7
Calculated Confidence Intervals of CVg Lower: 67.26, Upper: 100.63
Analytical CV 11.1
Calculated Confidence Intervals of Analytical CV Lower: 10.36, Upper: 11.96
Measurand Mean 0.73
Measurand Min
Measurand Max
Measurand SD