Alphafetoprotein

Included in meta analysis

Reference

Reference
Erden G, Barazi AO, Tezcan G and Yildirimkaya MM, 2008, Scand J Clin Lab Invest, 68, 212-8 , Biological variation and reference change vàlues of CA 19-9, CEA, AFP in sèrum of healthy individuals

Scoring

Total Score

C8,10

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis B
7. Steady State B
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
11. ANOVA B
12. CI A
13. No of Results B
14. Concentrations A
15. Total Score C8,10
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Alphafetoprotein
Unit ug / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 49
Number of Subjects included in BV estimation 45
Ethinicity Unknown
Age Mean / Median 33.1
Age Min 18.0
Age Max 60.0
Age SD
Number of Males 25
Number of Females 24
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 6
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 14
Interval Units Day
Sampling Times Start Time: 08:00
End Time: 10:00
Number of Samples 4
Average Number of Samples Used for BV Estimation 4.0
Average Number of Replicates 2.0
Estimates of CVi 26.67
Calculated Confidence Intervals of CVi Lower: 23.81, Upper: 30.30
Estimates of CVg 43.65
Calculated Confidence Intervals of CVg Lower: 35.39, Upper: 55.92
Analytical CV 3.0
Calculated Confidence Intervals of Analytical CV Lower: 2.72, Upper: 3.35
Measurand Mean 2.138
Measurand Min 0.736
Measurand Max 4.164
Measurand SD 0.993

Coding