Insulin

Reference

Reference
Lacher DA, Hughes JP and Carroll MD, 2005, Clin Chem, 51, 450-2 , Estimate of biological variation of laboratory analytes based on the third National Health and Nutrition Examination Survey

Scoring

Total Score

C5,7,8,10,12,13

Parameter Score
1. Scale A
2. Study Population B
3. Samples A
4. Measurand A
5. Pre-Analytical C
6. Replicate Analysis B
7. Steady State C
8. Outlier Analysis C
9. Normality B
10. Variance Homogeneity C
11. ANOVA B
12. CI C
13. No of Results C
14. Concentrations A
15. Total Score C5,7,8,10,12,13
Comment

Item Details

Parameter Score
Matrix Plasma
Measurand Insulin
Unit pmol / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 1177
Number of Subjects included in BV estimation 1177
Ethinicity Mixed
Age Mean / Median 30.8
Age Min
Age Max
Age SD
Number of Males
Number of Females
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 72.
Study Duration Units Month
Sampling Intervals, e.g. X sample(s) per Interval Unit
Interval Units Other
Sampling Times Start Time:
End Time:
Number of Samples 2
Average Number of Samples Used for BV Estimation 2.0
Average Number of Replicates 1.0
Estimates of CVi 25.2
Calculated Confidence Intervals of CVi Lower: 23.82, Upper: 26.60
Estimates of CVg
Calculated Confidence Intervals of CVg Lower: 53.43, Upper:
Analytical CV 13.0
Calculated Confidence Intervals of Analytical CV Lower: 11.92, Upper: 14.29
Measurand Mean 66.36
Measurand Min
Measurand Max
Measurand SD

Coding