EFLM Biological Varation Database : BIVAC Minimum Data Set for Procollagen type I N-terminal propeptide (PINP) EFLM Biological Variation

Procollagen type I N-terminal propeptide (PINP)

Reference

Cavalier E, Delanaye P and Moranne O, 2013, Am J Kidney Dis, 61(5), 845-8 , Variability of new bone mineral metabolism markers in patients treated with maintenance hemodialysis: implications for clinical decision making

Scoring

Total Score

C_{5,7,8,10,12,13}

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	C
6. Replicate Analysis	A
7. Steady State	C
8. Outlier Analysis	C
9. Normality	B
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	C
13. No of Results	C
14. Concentrations	A
15. Total Score	C_{5,7,8,10,12,13}
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Procollagen type I N-terminal propeptide (PINP)
Unit	ng / mL
Overall Analytical Principle Method	Chemiluminescence
Number of Subjects	17
Number of Subjects included in BV estimation	17
Ethinicity	Unknown
Age Mean / Median	60.0
Age Min	30.0
Age Max	86.0
Age SD
Number of Males	9
Number of Females	8
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length	6
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	2
Interval Units	Week
Sampling Times	Start Time: End Time:
Number of Samples	12
Average Number of Samples Used for BV Estimation
Average Number of Replicates	2.0
Estimates of CVi	10.5
Calculated Confidence Intervals of CVi	Lower: 9.43, Upper: 11.80
Estimates of CVg
Calculated Confidence Intervals of CVg	Lower: , Upper:
Analytical CV	4.7
Calculated Confidence Intervals of Analytical CV	Lower: 4.28, Upper: 5.20
Measurand Mean	124.0
Measurand Min
Measurand Max
Measurand SD	83.0

Coding

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