EFLM Biological Varation Database : BIVAC Minimum Data Set for Aldosterone EFLM Biological Variation

Aldosterone

Reference

Meijers WC, Van del Velde AR, Kobold ACM, et al, 2017, Eur J Hearth Failure , 19, 357-65 , Variability of biomarkers in patients with chronic heart failure and healthy controls

Originally from this reference: Eur J Hearth Failure , Meijers WC, Van del Velde AR, Kobold ACM, et al, 2017

ID: 0428

Scoring

Total Score

C_8,10

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	B
4. Measurand	A
5. Pre-Analytical	B
6. Replicate Analysis	A
7. Steady State	A
8. Outlier Analysis	C
9. Normality	A
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	A
13. No of Results	A
14. Concentrations	A
15. Total Score	C_8,10
Comment

Item Details

Parameter	Score
Matrix	Plasma
Measurand	Aldosterone
Unit	nmol / L
Overall Analytical Principle Method	Immunoassay; RIA
Number of Subjects	83
Number of Subjects included in BV estimation	83
Ethinicity	Unknown
Age Mean / Median	64.0
Age Min
Age Max
Age SD	10.0
Number of Males	79
Number of Females	4
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length	3
Study Duration Units	Week
Sampling Intervals, e.g. X sample(s) per Interval Unit	1
Interval Units	Week
Sampling Times	Start Time: End Time:
Number of Samples	3
Average Number of Samples Used for BV Estimation	3.0
Average Number of Replicates
Estimates of CVi	27.7
Calculated Confidence Intervals of CVi	Lower: 24.84, Upper: 31.19
Estimates of CVg	91.1
Calculated Confidence Intervals of CVg	Lower: 78.67, Upper: 107.91
Analytical CV	6.2
Calculated Confidence Intervals of Analytical CV	Lower: 4.84, Upper: 8.63
Measurand Mean	0.25
Measurand Min	0.14
Measurand Max	0.4
Measurand SD

Coding

Parameter	Score
Healthy Population	false
Adult Population	true
Weekly Samplings	true
Reviewed	true
Published	true
Gender for Meta-Analysis	Mixed
Snomed CT
NPU
LOINC
Comment

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