Troponin T, cardiac - high-sensitive (biweekly-monthly sampling)

Included in meta analysis


Meijers WC, Van del Velde AR, Kobold ACM, et al, 2017, Eur J Hearth Failure , 19, 357-65 , Variability of biomarkers in patients with chronic heart failure and healthy controls


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples C
4. Measurand C
5. Pre-Analytical B
6. Replicate Analysis B
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C3,4,8,10
Comment The authors do not indicate to discard results < LoD

Item Details

Parameter Score
Matrix Plasma
Measurand Troponin T, cardiac - high-sensitive (biweekly-monthly sampling)
Unit pg / mL
Overall Analytical Principle Method Chemiluminescence
Number of Subjects 28
Number of Subjects included in BV estimation 28
Ethinicity Unknown
Age Mean / Median 43.0
Age Min
Age Max
Age SD 13.0
Number of Males 14
Number of Females 14
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates
Estimates of CVi 16.0
Calculated Confidence Intervals of CVi Lower: 14.14, Upper: 18.43
Estimates of CVg 51.2
Calculated Confidence Intervals of CVg Lower: 40.39, Upper: 69.55
Analytical CV 1.5
Calculated Confidence Intervals of Analytical CV Lower: 1.10, Upper: 2.37
Measurand Mean 3.2
Measurand Min 3.0
Measurand Max 4.2
Measurand SD