Included in meta analysis


Meijers WC, Van del Velde AR, Kobold ACM, et al, 2017, Eur J Hearth Failure , 19, 357-65 , Variability of biomarkers in patients with chronic heart failure and healthy controls


Total Score


Parameter Score
1. Scale A
2. Study Population A
3. Samples B
4. Measurand A
5. Pre-Analytical B
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis C
9. Normality A
10. Variance Homogeneity C
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score C8,10

Item Details

Parameter Score
Matrix Plasma
Measurand Renin
Unit ng / L
Overall Analytical Principle Method Immunoassay; RIA
Number of Subjects 28
Number of Subjects included in BV estimation 28
Ethinicity Unknown
Age Mean / Median 43.0
Age Min
Age Max
Age SD 13.0
Number of Males 14
Number of Females 14
State of Well Being
Healthy (excl pregnant)
Study Duration Length 4
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 5
Average Number of Samples Used for BV Estimation 5.0
Average Number of Replicates
Estimates of CVi 30.1
Calculated Confidence Intervals of CVi Lower: 26.61, Upper: 34.66
Estimates of CVg 41.6
Calculated Confidence Intervals of CVg Lower: 31.92, Upper: 57.58
Analytical CV 2.3
Calculated Confidence Intervals of Analytical CV Lower: 1.68, Upper: 3.63
Measurand Mean 17.0
Measurand Min 13.0
Measurand Max 22.0
Measurand SD