EFLM Biological Varation Database : BIVAC Minimum Data Set for Alkaline phosphatase (ALP), liver type EFLM Biological Variation

Alkaline phosphatase (ALP), liver type

Reference

Alvarez L, Ricós C, Peris P, Guañabens N, Monegal A,Pons F and Ballesta AM, 2000, Bone, 26, 571-6 , Components of biological variation of biochemical markers of bone tumor in Paget’s bone disease

Scoring

Total Score

C_8,10,12

Parameter	Score
1. Scale	A
2. Study Population	A
3. Samples	A
4. Measurand	A
5. Pre-Analytical	A
6. Replicate Analysis	A
7. Steady State	A
8. Outlier Analysis	C
9. Normality	A
10. Variance Homogeneity	C
11. ANOVA	A
12. CI	C
13. No of Results	A
14. Concentrations	A
15. Total Score	C_8,10,12
Comment

Item Details

Parameter	Score
Matrix	Serum
Measurand	Alkaline phosphatase (ALP), liver type
Unit	U / L
Overall Analytical Principle Method	Spectrophotometry; Other
Number of Subjects	12
Number of Subjects included in BV estimation	12
Ethinicity	Unknown
Age Mean / Median	40.0
Age Min	28.0
Age Max	49.0
Age SD	6.2
Number of Males
Number of Females	12
State of Well Being	Non-healthy (excl pregnant)
Study Duration Length	1
Study Duration Units	Year
Sampling Intervals, e.g. X sample(s) per Interval Unit	3
Interval Units	Month
Sampling Times	Start Time: 8:00 End Time: 10:00
Number of Samples	4
Average Number of Samples Used for BV Estimation	4.0
Average Number of Replicates	2.0
Estimates of CVi	12.4
Calculated Confidence Intervals of CVi	Lower: 10.06, Upper: 16.13
Estimates of CVg	66.2
Calculated Confidence Intervals of CVg	Lower: 47.27, Upper: 109.58
Analytical CV	1.5
Calculated Confidence Intervals of Analytical CV	Lower: 1.25, Upper: 1.87
Measurand Mean	586.0
Measurand Min
Measurand Max
Measurand SD

Coding

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