Creatinine

Reference

Reference
Carobene A, Marino I, Coskun A, Serteser M, Unsai I, Guerra E, Barlett WA, Sandberg S, Aarsand AK, Sylte MS, Roraas T, Solvik UO, Fernández-Calle P, Diaz-Garzón J, Tosato F, Plebani M, Jonker N, Barla G and Ceriotti F, 2017, Clin Chem, 63, 1527-36 , The EuBIVAS Project: Within- and between-subject biological variation data for serum creatinine using enzymatic and alkaline picrate methods and implications for monitoring

Scoring

Total Score

A1,2,3,4,5,6,7,8,9,10,11,12,13,14

Parameter Score
1. Scale A
2. Study Population A
3. Samples A
4. Measurand A
5. Pre-Analytical A
6. Replicate Analysis A
7. Steady State A
8. Outlier Analysis A
9. Normality A
10. Variance Homogeneity A
11. ANOVA A
12. CI A
13. No of Results A
14. Concentrations A
15. Total Score A1,2,3,4,5,6,7,8,9,10,11,12,13,14
Comment

Item Details

Parameter Score
Matrix Serum
Measurand Creatinine
Unit mg / dL
Overall Analytical Principle Method Spectrophotometry; UV/VISIBLE
Number of Subjects 91
Number of Subjects included in BV estimation 91
Ethinicity Caucasian
Age Mean / Median
Age Min 21.0
Age Max 69.0
Age SD
Number of Males 38
Number of Females 53
State of Well Being
Healthy (excl pregnant)
Diseases
Study Duration Length 10
Study Duration Units Week
Sampling Intervals, e.g. X sample(s) per Interval Unit 1
Interval Units Week
Sampling Times Start Time:
End Time:
Number of Samples 10
Average Number of Samples Used for BV Estimation 9.46
Average Number of Replicates 1.96
Estimates of CVi 4.7
Calculated Confidence Intervals of CVi Lower: 4.35, Upper: 5.07
Estimates of CVg 19.0
Calculated Confidence Intervals of CVg Lower: 16.57, Upper: 22.25
Analytical CV 4.4
Calculated Confidence Intervals of Analytical CV Lower: 4.19, Upper: 4.63
Measurand Mean 0.74
Measurand Min 0.73
Measurand Max 0.75
Measurand SD

Coding