Reference
Carobene A, Marino I, Coskun A, Serteser M, Unsai I, Guerra E, Barlett WA, Sandberg S, Aarsand AK, Sylte MS, Roraas T, Solvik UO, Fernández-Calle P, Diaz-Garzón J, Tosato F, Plebani M, Jonker N, Barla G and Ceriotti F, 2017, Clin Chem, 63, 1527-36 , The EuBIVAS Project: Within- and between-subject biological variation data for serum creatinine using enzymatic and alkaline picrate methods and implications for monitoring
Parameter | Score |
---|---|
1. Scale | A |
2. Study Population | A |
3. Samples | A |
4. Measurand | A |
5. Pre-Analytical | A |
6. Replicate Analysis | A |
7. Steady State | A |
8. Outlier Analysis | A |
9. Normality | A |
10. Variance Homogeneity | A |
11. ANOVA | A |
12. CI | A |
13. No of Results | A |
14. Concentrations | A |
15. Total Score | A1,2,3,4,5,6,7,8,9,10,11,12,13,14 |
Comment |
Parameter | Score |
---|---|
Matrix | Serum |
Measurand | Creatinine |
Unit | mg / dL |
Overall Analytical Principle Method | Spectrophotometry; UV/VISIBLE |
Number of Subjects | 91 |
Number of Subjects included in BV estimation | 91 |
Ethinicity | Caucasian |
Age Mean / Median | |
Age Min | 21.0 |
Age Max | 69.0 |
Age SD | |
Number of Males | 38 |
Number of Females | 53 |
State of Well Being |
Healthy (excl pregnant)
|
Diseases | |
Study Duration Length | 10 |
Study Duration Units | Week |
Sampling Intervals, e.g. X sample(s) per Interval Unit | 1 |
Interval Units | Week |
Sampling Times | Start Time:
End Time: |
Number of Samples | 10 |
Average Number of Samples Used for BV Estimation | 9.46 |
Average Number of Replicates | 1.96 |
Estimates of CVi | 4.7 |
Calculated Confidence Intervals of CVi | Lower: 4.35, Upper: 5.07 |
Estimates of CVg | 19.0 |
Calculated Confidence Intervals of CVg | Lower: 16.57, Upper: 22.25 |
Analytical CV | 4.4 |
Calculated Confidence Intervals of Analytical CV | Lower: 4.19, Upper: 4.63 |
Measurand Mean | 0.74 |
Measurand Min | 0.73 |
Measurand Max | 0.75 |
Measurand SD |